H. pylori Genome Project (HpGP)
H. pylori infects half the world’s population and is the primary cause of gastric cancer. The HpGP will describe the worldwide genomic and epigenomic variation of H. pylori to identify molecular determinants of carcinogenicity. DCEG investigators are sequencing 1000 H. pylori strains from individuals with and without gastric cancer residing in 40 different countries. An international team of experts is collaborating on analyses of these complex molecular data. In collaboration with the Division of Gastroenterology at Vanderbilt University, DCEG is building a biobank with all strains for mechanistic studies.