DCEG researchers investigate the cancer risk from air pollutants. In particular, they are exploring the lung cancer risk from exposure to smoke from open fires in homes, a major health risk in developing countries. These efforts include the study of variation in genes that activate and detoxify chemicals in the smoke, DNA repair and cell cycle control, and potential gene-environment interactions.
In March 2012, the National Cancer Institute (NCI) and the National Institute for Occupational Safety and Health (NIOSH) completed a retrospective cohort mortality and nested case-control study of 12,315 workers at eight non-metal mining facilities to investigate risk of lung cancer in relation to quantitative measures of historical exposure to diesel exhaust, after taking into account smoking and other lung cancer risk factors
Investigation of the role of indoor air pollution from solid fuel use in lung cancer in Asia
Studies of cancer risk associated with exposure to outdoor air pollutants arising from traffic, industrial, and agricultural sources, including ultrafine particulate matter and dioxins
A case-control study of lung cancer and residential radon exposure in which investigators carried out both standard year-long air measurements and CR-39 alpha detector measurements (call surface monitors)