Predictors of Outcomes after Allogeneic Hematopoietic Cell Transplantation (HCT)

Testing for IBMFS in Patients with SAA

Unrecognized inherited bone marrow failure syndromes influence treatment outcomes.

Allogeneic hematopoietic cell transplant (HCT) is the treatment of choice for many severe life-threatening malignant or non-malignant diseases of the hematopoietic system. Despite significant improvement in survival after HCT, patient still suffer high mortality and morbidity risk from disease relapse or transplant-related complications.

Studies in the Clinical Genetics Branch aim to improve patient survival by identifying biomarkers that can guide donor selection or refine patient risk stratification. Ongoing research includes patients receiving HCT for severe aplastic anemia or myeloid neoplasms.

For more information, contact  Shahinaz Gadalla.

Clinical Genetics Branch - Research Areas