This study is designed to improve our understanding of radiation-related risk for intracranial tumors of the brain and nervous system through a pooled analysis of 16 epidemiological studies that have a reasonable number of exposed study subjects, individual estimates of radiation dose to the brain and different reasons for radiation exposure. By including a large number of individuals exposed over a wide range of doses, at different dose rates and ages, we hope to increase precision to quantify the overall dose-response relationship for specific histological types of tumors (glioma, meningioma and acoustic neuroma) and to address effects of possible modifying factors. In particular, results would aid in the assessment of risks related to CT scans, a question of considerable public health importance in light of their growing use.
For more information, contact Lene Veiga.