Characterization of Renal Cell Carcinoma Uncommon Histological Subtypes

In collaboration with several institutions in Italy, DCEG researchers study uncommon renal cancer histological subtypes, including papillary renal cell carcinomas type 1 and type 2, collecting ducts, chromophobe renal cell carcinomas, and high-grade urothelial carcinomas. Clinical studies assess major risk factors associated with these subtypes, the diseases' outcomes, and the optimal length of follow-up after surgery. Additional studies investigate the genomic landscape and the features of the tumor microenvironment of each histological subtype.

For more information, contact Maria Teresa Landi.

• The genomic and epigenomic evolutionary history of papillary renal cell carcinomas. Nat Commun 2021; Zhu B, Poeta ML, Costantini M, et al.