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Discovering the causes of cancer and the means of prevention

PanScan Study

PanScan is a multi-stage genome-wide association study (GWAS) of pancreatic cancer conducted within the framework of the NCI Cohort Consortium. Investigators have conducted three GWAS phases, PanScan I, II and III, that have led to the discovery of 23 signals at 19 genomic loci that are associated with risk for pancreatic cancer. Additional epidemiologic and genetic studies using data from these initial studies are now underway.

The next phase of the project will analyze more than 5,000 pancreatic cancer cases from multiple cohorts, case control and population-based studies, including those from PanScan I-III, to discover novel regions of the genome associated with pancreatic cancer susceptibility.

For more information, contact:
Rachael Stolzenberg-Solomon
Metabolic Epidemiology Branch - Research Areas

Laufey Amundadottir
Laboratory of Translational Genomics - Research Areas