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Discovering the causes of cancer and the means of prevention

PanScan Study

PanScan is a multi-stage genome-wide association study (GWAS) of pancreatic cancer conducted within the framework of the NCI Cohort Consortium. Investigators have conducted three GWAS phases, PanScan I, II and III, and a meta-analysis with the Pancreatic Cancer Case-Control Consortium (PanC4) GWAS that collectively have led to the discovery of 20 genomic signals associated with risk for pancreatic cancer. Additional epidemiologic and genetic studies using data from these initial studies are now underway.

The next phase of the project will analyze additional pancreatic cancer cases from multiple cohorts, case-control, population-based, and biobank studies—including those from PanScan I-III—to discover novel regions of the genome associated with pancreatic cancer susceptibility.

For more information, contact:
Rachael Stolzenberg-Solomon
Metabolic Epidemiology Branch - Research Areas

Laufey Amundadottir
Laboratory of Translational Genomics - Research Areas