Testes
DCEG researchers conduct studies on cancer of the testes, also known as testicular cancer. Testicular cancer is most common in young or middle-aged men. Most testicular cancers begin in germ cells and are called testicular germ cell tumors. Selected studies include:
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Familial Testicular Cancer Study
A study evaluating the role of testicular microlithiasis in familial testicular cancer
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PFAS Exposure and Risk of Cancer
DCEG investigators in the Occupational and Environmental Epidemiology Branch (OEEB) have developed a portfolio of research aimed at identifying cancer-types associated with per- and polyfluoroalkyl substances (PFAS). These studies are innovative for their direct assessment of exposure using banked serum specimens as well as their evaluation of risks at varying exposure levels, from occupational exposure to those found in the general population or among military personnel.
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Testicular Cancer among Military Servicemen: The STEED Study
A case-control study of testicular cancer among military servicemen
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Testicular Cancer Consortium (TECAC)
A consortium of international studies to examine genetic susceptibility to testicular cancer
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Testicular Cancer Research in the Metabolic Epidemiology Branch
MEB Testicular Cancer Studies
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Testicular Germ Cell Tumor Methylation Study
A study that will compare the methylation profiles of specific testicular germ cell tumor histologies with one another and with ‘normal’ tissue
Research News
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PFAS Linked with Testicular Cancer Risk in U.S. Air Force ServicemenDr. Mark Purdue and colleagues report a link between serum PFOS levels and testicular cancer.
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CHEK2 Identified as Intermediate-risk Driver of Testicular Germ Cell Tumor SusceptibilityGermline variants in CHEK2 associated with risk of familial testicular germ cell tumors (TGCT).