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Discovering the causes of cancer and the means of prevention

Perinatal Exposures and Thyroid Cancer Risk

For reasons that remain unexplained, thyroid cancer incidence is much higher in women than men, and this sex difference peaks during the reproductive years. The National Cancer Institute (NCI) is linking thyroid cancer incidence data from the national cancer and medical birth registries in Norway, Sweden, Denmark, and Finland, to explore whether perinatal characteristics and exposures, including parental smoking and pregnancy complications, are related to risk of thyroid cancer in mothers and their offspring. 

In a separate investigation, the NCI is leading a study to assess whether high or low levels of sex steroid hormones and thyroid hormones measured in early pregnancy are associated with later risk of thyroid cancer in these women.

For more information, contact Cari Kitahara.

Radiation Epidemiology Branch - Research Areas

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