Skip to main content
An official website of the United States government
Government Funding Lapse
Because of a lapse in government funding, the information on this website may not be up to date, transactions submitted via the website may not be processed, and the agency may not be able to respond to inquiries until appropriations are enacted.

The NIH Clinical Center (the research hospital of NIH) is open. For more details about its operating status, please visit cc.nih.gov.

Updates regarding government operating status and resumption of normal operations can be found at opm.gov.

Email

Cancer Surveillance Research

No Image Placeholder
Celebrating Fifty Years of SEER

DCEG scientists celebrate the 50th anniversary of the Surveillance, Epidemiology, and End Results (SEER) program.

Elucidating Etiologic Heterogeneity, Current Patterns, and Future Trends

DCEG investigators developed a broad-ranging, multi-faceted program of descriptive studies with major themes including the evaluation of tumor heterogeneity, current and future trends, and second cancers. Recent highlights include:

  • One of the first demonstrations of breast cancer heterogeneity by hormone receptor expression, as well as novel projections of breast cancer trends by estrogen receptor status was evaluated using SEER data.
  • A series of studies that showed a major emerging role for human papillomavirus (HPV) infection in the epidemiology of head and neck squamous cell carcinomas, especially among men. Novel projections that DCEG investigators developed for those studies have influenced key policy deliberations pertaining to HPV vaccination of boys in the U.S.

Future Goals

Investigators will continue to explore population heterogeneity, disparities, geographic variation, and international patterns through three key strategies:

  1. Comprehensive comparative analyses of incidence, mortality, and survival patterns for subtypes of many common and less common malignancies;
  2. Analyses of time trends, calendar-period and birth-cohort effects, risk factor patterns, molecular data, and incidence of new malignancies among cancer survivors;
  3. Extensive extramural collaborative efforts with the American Cancer Society (ACS), International Agency for Research on Cancer (IARC), North American Association of Central Cancer Registries (NAACCR), Center for Disease Control and Prevention (CDC), and Danish Breast Cancer Cooperative Group (DBCG). 

For more information, contact:

Meredith Shiels
Infections and Immunoepidemiology Branch

Email