DCEG investigators in the Radiation Epidemiology Branch (REB) investigators coordinated a study of thyroid cancer and other thyroid diseases in a cohort of 25,000 persons from Belarus and Ukraine who were exposed in childhood to fallout from the Chernobyl accident. Each member of this unique cohort had individual direct thyroid measurements of 131I activity in thyroid gland taken shortly after the accident. Recent efforts have been focused on improving estimated radiation doses to the thyroid from all exposure pathways and evaluating uncertainties in thyroid doses from intake of 131I, which contributes about 90% of the total thyroid dose.
Key improvements included:
The average thyroid dose was 0.65 Gy (0.00035 – 42 Gy) in 13,204 persons in the Ukrainian screening cohort and an average thyroid dose of 0.68 Gy (0.0005 – 39 Gy) in 11,732 persons in the Belarusian cohort. These dose estimates were used to evaluate radiation-associated risk of thyroid cancer that incorporates estimates of uncertainty.
For more information, contact Dr. Vladimir Drozdovitch.