Breast Cancer Studies in the Integrative Tumor Epidemiology Branch

DCEG researchers conduct studies on breast cancer, a cancer that usually forms in the breast ducts (tubes that carry milk to the nipple) and lobules (glands that make milk). Breast cancer occurs in both men and women, although male breast cancer is rare. Selected studies in the Integrative Tumor Epidemiology Branch include:

Breast Cancer Among Asian Women
Studies of breast tissues, risk factors, clinical data, breast density, blood or saliva for germline DNA to identify distinct molecular alterations in tumors and adjacent benign breast tissues among Asian women and to examine the associations of molecular changes with genetic and environmental risk factors, breast tissue composition and density, and breast cancer subtypes.

Breast Cancer Case-Control Study in Poland
A population-based case-control study of breast cancer in Poland that combines state-of-the art techniques of exposure assessment and collection of biological specimens.

Breast Cancer Detection Demonstration Project Follow-up Study
A follow-up study of women who were participants in the Breast Cancer Detection Demonstration Project.

Breast CAncer STratification (BCAST) Project
A large-scale evaluation of how genetic and environmental risk factors, molecular tumor characteristics and clinical progression interrelate.

Breast Radiology Evaluation and Study of Tissues (BREAST) Stamp Project
A study that aims to characterize the radiologic, histologic, and molecular features of dense breast tissue.

Columbia, Missouri Serum Bank Follow-up Study
A study established as part of NCI's Biological Markers Project to identify serum markers for breast cancer.

Confluence Project
A large research resource that aims to uncover breast cancer genetics through genome-wide association studies.

Ghana Breast Health Study
The Ghana Breast Health Study is a multidisciplinary case-control study of breast cancer in Ghana, West Africa.

Kaiser Permanente Breast Cancer Survivors Cohort
The DCEG Kaiser Permanente Breast Cancer Survivors Cohort was initiated as a transdisciplinary resource to investigate the risk of contralateral breast cancer and cardiovascular disease.

Kenya Breast Cancer Study
A study that utilizes molecular and genomic approaches to investigate breast tumors and the tumor microenvironment among African women.

Outdoor Air Pollution and Terminal Duct Lobular Involution of the Normal Breast
A study investigating the association between exposure to fine particulate matter (PM 2.5) and terminal duct lobular involution (TDLU) of the normal breast.

Risk Factor Heterogeneity in Breast Cancer
A study of breast cancer risk factors and clinical features, focusing on women living in China and Malaysia.

Terminal Duct Lobular Unit Involution of the Normal Breast
A molecular epidemiologic study of terminal duct lobular units of the normal breast, conducted in collaboration with the Susan G. Komen® Tissue Bank.

Ultrasound Study of the Effects of Tamoxifen on Breast Tissue
A study using ultrasound tomography to define the time course of volumetric breast density changes among women receiving tamoxifen treatment.