Research Highlights - News Updates
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Radiation Dose to Medical Staff Performing Fluoroscopically Guided Interventional Procedures
A new study finds ionizing radiation exposure to workers performing or assisting in fluoroscopically guided interventional (FGI) procedures are among the highest in medical practice. The results were published November 26, 2019 in the journal Radiology.
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Obesity and Overweight Associated with Rise in Papillary Thyroid Cancer Rates
Overweight and obesity may have contributed to the rapid rise in papillary thyroid cancer (PTC) incidence according to findings published Oct 22, 2019 in the Journal of the National Cancer Institute.
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Life-Gained Approach to Lung Cancer Screening May Increase Life Expectancy
Life-gained approach to lung cancer screening resulted in the greatest increase in life expectancy compared to risk-based strategies and current guidelines, according to findings published in Annals of Internal Medicine on October 22, 2019.
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NIH-AARP Diet and Health Study Reaches Milestone
Nearly 25 years ago, NCI investigators mailed over three million members of the AARP a food frequency questionnaire to examine the relationship between diet, lifestyle, and cancer risk among older Americans. With the response of over half a million people, the NCI launched the NIH-AARP Diet and Health Study, a cohort that was, and remains, the largest prospective in-depth study on diet and health.
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Bone and Soft Tissue Sarcoma Risk Patterns Among Survivors of Hereditary Retinoblastoma
Long-term risk of bone and soft tissue sarcomas after treatment for hereditary retinoblastoma varies by age, location and sex, according to a study published in the Journal of Clinical Oncology on October 17, 2019.
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Aspirin Use Associated with Increased Survival in Biliary Tract Cancer
Aspirin use after biliary tract cancer (BTC) diagnosis was associated with increased patient survival, according to a study by DCEG investigators published in JAMA Oncology on October 17, 2019.
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New Reports Highlight the Critical Role of Physical Activity for Cancer Prevention, Treatment, and Survival
Roundtable on Exercise and Cancer updates the evidence on physical activity for the prevention of multiple cancer types, and the importance of exercise for cancer patients and survivors to improve their physical and psychological health.
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HPV Vaccine May Provide Men with Herd Immunity against Oral HPV Infections
Oral HPV infections among unvaccinated men dropped 37% in 2009-2016 which may be a result of herd immunity by the HPV vaccine.
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Scientific Highlights July - October 2019
Selected scientific papers published by DCEG scientists July - October 2019
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Validation of New High Throughput, Low Cost HPV Test for Cervical Cancer Prevention
High-throughput, low cost genotyping assay, TypeSeq, detects cervical precancer and estimates HPV vaccination efficacy.
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Risk for Treatment-related Leukemia after Chemotherapy for Childhood Cancer has Increased Over Last 45 years
Risk of therapy-related myelodysplastic syndrome and acute myeloid leukemia (tMDS/AML) after initial chemotherapy for childhood cancer has significantly increased between 1975 and 2015, according to a new analysis by Pragati Advani, Ph.D., and colleagues.
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MGUS Immune Markers Predict Risk of Progression to Multiple Myeloma
Longitudinal prospective study links changes in monoclonal gammopathy of undetermined significance (MGUS) immune markers with progression to multiple myeloma.
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Breastfeeding Associated with Lower Breast Cancer Risk in Women with Li-Fraumeni Syndrome
Breastfeeding for at least seven months was associated with 43 percent reduced risk of breast cancer in women with the cancer predisposition syndrome, Li-Fraumeni Syndrome (LFS).
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NCI study finds long-term increased risk of cancer death following common treatment for hyperthyroidism
Radioactive iodine (RAI) treatment for hyperthyroidism is associated with increased risk of death from solid cancers, including breast cancer, new study finds.
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Antibodies to HPV16 Measured in Blood up to 28 Years Prior to Oropharyngeal Cancer Diagnosis
Human papillomavirus-16-E6 antibodies can be detected in the blood of people with oropharyngeal cancer up to 28 years prior to diagnosis, according to new study by the National Cancer Institute and the International Agency for Research on Cancer.
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Higher Risk Threshold Better for Selecting Ever-Smokers for Lung Cancer Screening
Researchers determined a higher risk threshold for selecting ever-smokers for screening with low-dose CT could lower the ratio of individuals screened to prevent one lung cancer death, improving on US Preventive Services Task Force guidelines.
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Study shows incidence rates of aggressive subtypes of uterine cancer rising
New study shows that U.S. incidence rates for aggressive subtypes of uterine cancer rose rapidly among women age 30 to 79 from 2000 to 2015. Study also reveals racial disparities for these subtypes.
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Dual-Staining Outperforms Cytology for Follow-up of HPV-positive Women in Cervical Cancer Screening Programs
Dual staining for p16/Ki-67 outperformed cytology in detecting precancer among HPV-positive women while referring fewer women to secondary screening, visual inspection of the cervix with magnification, known as colposcopy.
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Longer Intervals Between Lung Cancer Screens Could Reduce False-Positives for Low-Risk Patients
A personalized approach for choosing how long to wait between lung cancer screenings could be an efficient way to reduce false-positives and other harms.